A low dose of fermented soy germ alleviates gut barrier injury, hyperalgesia and faecal protease activity in a rat model of inflammatory bowel disease.

Pro-inflammatory cytokines like macrophage migration inhibitory factor (MIF), IL-1β and TNF-α predominate in inflammatory bowel diseases (IBD) and TNBS colitis. Increased levels of serine proteases activating protease-activated receptor 2 (PAR-2) are found in the lumen and colonic tissue of IBD pati...

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Main Authors: Lara Moussa, Valérie Bézirard, Christel Salvador-Cartier, Valérie Bacquié, Corinne Lencina, Mathilde Lévêque, Viorica Braniste, Sandrine Ménard, Vassilia Théodorou, Eric Houdeau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3498131?pdf=render