Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in <i>Pgc-1α</i> Deficient Murine Atria

Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in <i>Pgc-1α</i> Deficient Murine Atria

Increases in the prevalence of obesity, insulin resistance, and metabolic syndrome has led to the increase of atrial fibrillation (AF) cases in the developed world. These AF risk factors are associated with mitochondrial dysfunction, previously modelled using peroxisome proliferator activated recept...

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Bibliographic Details
Main Authors: Karan R. Chadda, Charlotte E. Edling, Haseeb Valli, Shiraz Ahmad, Christopher L.-H. Huang, Kamalan Jeevaratnam
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
peroxisome proliferator activated receptor-γ (PPARγ) coactivator-1 transcriptional coactivator (Pgc-1)
quantitative PCR
ion channels
mitochondria
arrhythmias
Online Access:https://www.mdpi.com/1422-0067/19/11/3450

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https://www.mdpi.com/1422-0067/19/11/3450

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