High resolution systematic digital histological quantification of cardiac fibrosis and adipose tissue in phospholamban p.Arg14del mutation associated cardiomyopathy.

High resolution systematic digital histological quantification of cardiac fibrosis and adipose tissue in phospholamban p.Arg14del mutation associated cardiomyopathy.

Myocardial fibrosis can lead to heart failure and act as a substrate for cardiac arrhythmias. In dilated cardiomyopathy diffuse interstitial reactive fibrosis can be observed, whereas arrhythmogenic cardiomyopathy is characterized by fibrofatty replacement in predominantly the right ventricle. The p...

Full description

Bibliographic Details
Main Authors: Johannes M I H Gho, René van Es, Nikolas Stathonikos, Magdalena Harakalova, Wouter P te Rijdt, Albert J H Suurmeijer, Jeroen F van der Heijden, Nicolaas de Jonge, Steven A J Chamuleau, Roel A de Weger, Folkert W Asselbergs, Aryan Vink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986391?pdf=render

Internet

http://europepmc.org/articles/PMC3986391?pdf=render

Similar Items