HIV Reactivation in Latently Infected Cells with Virological Synapse-Like Cell Contact

HIV reactivation from latency is induced by cytokines but also by cell contact with other cells. To better understand this, J1.1 cells, a latent HIV-1-infected Jurkat derivative, were cocultured with its parental Jurkat. J1.1 cells became p17MA-positive and produced a high level of HIV p24CA antigen...

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Bibliographic Details
Main Authors: Toshiki Okutomi, Satoko Minakawa, Riku Hirota, Koko Katagiri, Yuko Morikawa
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/4/417