Selective targeting of tumor associated macrophages in different tumor models.

Selective targeting of tumor associated macrophages in different tumor models.

Tumor progression largely depends on the presence of alternatively polarized (M2) tumor-associated macrophages (TAMs), whereas the classical M1-polarized macrophages can promote anti-tumorigenic immune responses. Thus, selective inhibition of M2-TAMs is a desirable anti-cancer approach in highly res...

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Bibliographic Details
Main Authors: Bianca Kakoschky, Thomas Pleli, Christian Schmithals, Stefan Zeuzem, Bernhard Brüne, Thomas J Vogl, Horst-Werner Korf, Andreas Weigert, Albrecht Piiper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5814016?pdf=render

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http://europepmc.org/articles/PMC5814016?pdf=render

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