Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells
Abstract Background Antimicrobial T cells play key roles in the disease progression of cancers arising in mucosal epithelial tissues, such as the colon. However, little is known about microbe-reactive T cells within human breast ducts and whether these impact breast carcinogenesis. Methods Epithelia...
Main Authors: | Nicholas A. Zumwalde, Jill D. Haag, Michael N. Gould, Jenny E. Gumperz |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | Breast Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13058-018-1036-5 |
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