Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity.

Although toll-like receptor (TLR) signals are critical for promoting antigen presenting cell maturation, it remains unclear how stimulation via different TLRs influence dendritic cell (DC) function and the subsequent adaptive response in vivo. Furthermore, the relationship between TLR-induced cytoki...

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Bibliographic Details
Main Authors: Albert C C Lin, Dilan Dissanayake, Salim Dhanji, Alisha R Elford, Pamela S Ohashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3171407?pdf=render