Mitochondrial Protein Synthesis and mtDNA Levels Coordinated through an Aminoacyl-tRNA Synthetase Subunit

Mitochondrial Protein Synthesis and mtDNA Levels Coordinated through an Aminoacyl-tRNA Synthetase Subunit

Summary: The aminoacylation of tRNAs by aminoacyl-tRNA synthetases (ARSs) is a central reaction in biology. Multiple regulatory pathways use the aminoacylation status of cytosolic tRNAs to monitor and regulate metabolism. The existence of equivalent regulatory networks within the mitochondria is unk...

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Bibliographic Details
Main Authors: Daria Picchioni, Albert Antolin-Fontes, Noelia Camacho, Claus Schmitz, Alba Pons-Pons, Marta Rodríguez-Escribà, Antigoni Machallekidou, Merve Nur Güler, Panagiota Siatra, Maria Carretero-Junquera, Alba Serrano, Stacy L. Hovde, Philip A. Knobel, Eva M. Novoa, Maria Solà-Vilarrubias, Laurie S. Kaguni, Travis H. Stracker, Lluís Ribas de Pouplana
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719303298

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http://www.sciencedirect.com/science/article/pii/S2211124719303298

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