Metabolic network discovery by top-down and bottom-up approaches and paths for reconciliation

The primary focus in the network-centric analysis of cellular metabolism by systems biology approaches is to identify the active metabolic network for the condition of interest. Two major approaches are available for the discovery of the condition-specific metabolic networks. One approach starts fro...

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Bibliographic Details
Main Authors: Tunahan eCakir, Mohammad Jafar Khatibipour
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00062/full