C21orf91 Regulates Oligodendroglial Precursor Cell Fate—A Switch in the Glial Lineage?

C21orf91 Regulates Oligodendroglial Precursor Cell Fate—A Switch in the Glial Lineage?

Neuropathological diseases of the central nervous system (CNS) are frequently associated with impaired differentiation of the oligodendroglial cell lineage and subsequent alterations in white matter structure and dynamics. Down syndrome (DS), or trisomy 21, is the most common genetic cause for cogni...

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Bibliographic Details
Main Authors: Laura Reiche, Peter Göttle, Lydie Lane, Paula Duek, Mina Park, Kasum Azim, Jana Schütte, Anastasia Manousi, Jessica Schira-Heinen, Patrick Küry
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
white matter deficits
gliogenesis
cell fate
down syndrome
neuroregeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.653075/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.653075/full

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