Neuronal impairment following chronic Toxoplasma gondii infection is aggravated by intestinal nematode challenge in an IFN-γ-dependent manner

Neuronal impairment following chronic Toxoplasma gondii infection is aggravated by intestinal nematode challenge in an IFN-γ-dependent manner

Abstract Background It has become increasingly evident that the immune and nervous systems are closely intertwined, relying on one another during regular homeostatic conditions. Prolonged states of imbalance between neural and immune homeostasis, such as chronic neuroinflammation, are associated wit...

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Bibliographic Details
Main Authors: Timothy French, Henning Peter Düsedau, Johannes Steffen, Aindrila Biswas, Norus Ahmed, Susanne Hartmann, Thomas Schüler, Björn H. Schott, Ildiko Rita Dunay
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Neuroinflammation
Subjects:
Toxoplasma gondii
Heligmosomoides polygyrus
Co-infection
Immunomodulation
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-019-1539-8

Internet

http://link.springer.com/article/10.1186/s12974-019-1539-8

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