Homologous and heterologous protection of nonhuman primates by Ebola and Sudan virus-like particles.

Homologous and heterologous protection of nonhuman primates by Ebola and Sudan virus-like particles.

Filoviruses cause hemorrhagic fever resulting in significant morbidity and mortality in humans. Several vaccine platforms that include multiple virus-vectored approaches and virus-like particles (VLPs) have shown efficacy in nonhuman primates. Previous studies have shown protection of cynomolgus mac...

Full description

Bibliographic Details
Main Authors: Kelly L Warfield, John M Dye, Jay B Wells, Robert C Unfer, Frederick W Holtsberg, Sergey Shulenin, Hong Vu, Dana L Swenson, Sina Bavari, M Javad Aman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0118881

Internet

https://doi.org/10.1371/journal.pone.0118881

Similar Items