The SmpB C-terminal tail helps tmRNA to recognize and enter stalled ribosomes

In bacteria, transfer-messenger RNA (tmRNA) and SmpB comprise the most common and effective system for rescuing stalled ribosomes. Ribosomes stall on mRNA transcripts lacking stop codons and are rescued as the defective mRNA is swapped for the tmRNA template in a process known as trans-translation....

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Bibliographic Details
Main Authors: Mickey R. Miller, Allen R. Buskirk
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2014.00462/full