Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice.

Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice.

Hydrogen sulfide (H(2)S), a novel gaseous messenger, is synthesized endogenously from L-cysteine by two pyridoxal-5'-phosphate-dependent enzymes, cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE). S-propargyl-cysteine (SPRC) is a slow H(2)S releasing drug that provides cysteine, a...

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Bibliographic Details
Main Authors: Jenab N Sidhapuriwala, Akhil Hegde, Abel D Ang, Yi Zhun Zhu, Madhav Bhatia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3291555?pdf=render

Internet

http://europepmc.org/articles/PMC3291555?pdf=render

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