SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.

Components of promyelocytic leukaemia (PML) nuclear bodies (ND10) are recruited to sites associated with herpes simplex virus type 1 (HSV-1) genomes soon after they enter the nucleus. This cellular response is linked to intrinsic antiviral resistance and is counteracted by viral regulatory protein I...

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Bibliographic Details
Main Authors: Delphine Cuchet-Lourenço, Chris Boutell, Vera Lukashchuk, Kyle Grant, Amanda Sykes, Jill Murray, Anne Orr, Roger D Everett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21779164/?tool=EBI