The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence.
MicroRNAs (miRNAs) are short 20-22 nucleotide RNA molecules that act as negative regulators of gene expression via translational repression: they have been shown to play a role in development, proliferation, stress response, and apoptosis. The transcriptional regulator LRF (Leukemia/lymphoma Related...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-07-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2435600?pdf=render |