Oxidatively modified RNA in mild cognitive impairment

Oxidatively modified RNA in mild cognitive impairment

Studies show increased oxidative damage in the brains of subjects with Alzheimer’s disease (AD) and mild cognitive impairment (MCI). To determine if RNA oxidation occurs in MCI, sections of hippocampus/parahippocampal gyrus (HPG) from 5 MCI, 5 late stage AD (LAD) and 5 age-matched normal control (NC...

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Bibliographic Details
Main Authors: Mark A. Lovell, William R. Markesbery
Format: Article
Language:English
Published: Elsevier 2008-02-01
Series:Neurobiology of Disease
Subjects:
RNA
Oxidative stress
Alzheimer’s disease
Mild cognitive impairment
Lipid peroxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107001957

Internet

http://www.sciencedirect.com/science/article/pii/S0969996107001957

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