Global and local architecture of the mammalian microRNA-transcription factor regulatory network.
microRNAs (miRs) are small RNAs that regulate gene expression at the posttranscriptional level. It is anticipated that, in combination with transcription factors (TFs), they span a regulatory network that controls thousands of mammalian genes. Here we set out to uncover local and global architectura...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-07-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1914371?pdf=render |