Acetylcholinesterase and monoamine oxidase-B inhibitory activities by ellagic acid derivatives isolated from Castanopsis cuspidata var. sieboldii

Abstract Among 276 herbal extracts, a methanol extract of Castanopsis cuspidata var. sieboldii stems was selected as an experimental source for novel acetylcholinesterase (AChE) inhibitors. Five compounds were isolated from the extract by activity-guided screening, and their inhibitory activities ag...

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Bibliographic Details
Main Authors: Jong Min Oh, Hyun-Jae Jang, Myung-Gyun Kang, Soobin Song, Doo-Young Kim, Jung‑Hee Kim, Ji-In Noh, Jong Eun Park, Daeui Park, Sung-Tae Yee, Hoon Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93458-4