Impacts of AD-Related ABCA7 and CLU Variants on Default Mode Network Connectivity in Healthy Middle-Age Adults

Impacts of AD-Related ABCA7 and CLU Variants on Default Mode Network Connectivity in Healthy Middle-Age Adults

ObjectiveTo investigate the impact of Alzheimer’s disease (AD)-related risk gene (ATP-binding cassette A7-ABCA7 and Clusterin-CLU) on the functional connectivity pattern of default mode network (DMN) in healthy middle-age adults.MethodsA total of 147 healthy middle-aged volunteers were enrolled in t...

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Bibliographic Details
Main Authors: Xin Yuan Zhang, Yun Fei Wang, Li Juan Zheng, Han Zhang, Li Lin, Guang Ming Lu, Long Jiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
ATP-binding cassette A7
clusterin
default mode network
Alzheimer’s disease
middle-age adults
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00145/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2020.00145/full

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