The Curcumin Analogue, MS13 (1,5-Bis(4-hydroxy-3- methoxyphenyl)-1,4-pentadiene-3-one), Inhibits Cell Proliferation and Induces Apoptosis in Primary and Metastatic Human Colon Cancer Cells

The Curcumin Analogue, MS13 (1,5-Bis(4-hydroxy-3- methoxyphenyl)-1,4-pentadiene-3-one), Inhibits Cell Proliferation and Induces Apoptosis in Primary and Metastatic Human Colon Cancer Cells

The cytotoxic and apoptotic effects of turmeric (Curcuma longa) on colon cancer have been well documented but specific structural modifications of curcumin have been shown to possess greater growth-suppressive potential on colon cancer than curcumin. Therefore, the aim of this study is to identify t...

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Bibliographic Details
Main Authors: Nor Isnida Ismail, Iekhsan Othman, Faridah Abas, Nordin H. Lajis, Rakesh Naidu
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
curcumin analogue
diarylpentanoid (DAP)
colon cancer
cell proliferation
apoptosis
1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one
Online Access:https://www.mdpi.com/1420-3049/25/17/3798

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https://www.mdpi.com/1420-3049/25/17/3798

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