A Novel Chimeric Endolysin with Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus

A Novel Chimeric Endolysin with Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus

Cysteine/histidine-dependent amidohydrolase/peptidase (CHAP) and amidase are known as catalytic domains of the bacteriophage-derived endolysin LysK and were previously reported to show lytic activity against methicillin-resistant Staphylococcus aureus (MRSA). In the current study, the in silico desi...

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Bibliographic Details
Main Authors: Hamed Haddad Kashani, Hossein Fahimi, Yasaman Dasteh Goli, Rezvan Moniri
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Staphylococcus aureus
endolysin
antibacterial agent
CHAP-amidase domain
in silico analysis
antibiotic resistant
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00290/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00290/full

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