Effects of the loss of estrogen on the heart’s hypertrophic response to chronic left ventricle volume overload in rats

Aortic valve regurgitation (AR) can result in heart failure from chronic overloading of the left ventricle (LV). Little is known of the role of estrogens in the LV responses to this condition. The aim of the study was to compare LV remodeling in female rats with severe AR in absence of estrogens by...

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Bibliographic Details
Main Authors: Elisabeth Walsh-Wilkinson, Catherine Beaumont, Marie-Claude Drolet, Ève-Marie Roy, Charlie Le Houillier, Jonathan Beaudoin, Marie Arsenault, Jacques Couet
Format: Article
Language:English
Published: PeerJ Inc. 2019-10-01
Series:PeerJ
Subjects:
Rat
Online Access:https://peerj.com/articles/7924.pdf