Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis

Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis

ABSTRACT Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving loss of motor neurons and having no known cure and uncertain etiology. Several studies have drawn connections between altered retrotransposon expression and ALS. Certain features of the LINE-1 (L1)...

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Main Authors: Gavin C. Pereira, Laura Sanchez, Paul M. Schaughency, Alejandro Rubio-Roldán, Jungbin A. Choi, Evarist Planet, Ranjan Batra, Priscilla Turelli, Didier Trono, Lyle W. Ostrow, John Ravits, Haig H. Kazazian, Sarah J. Wheelan, Sara R. Heras, Jens Mayer, Jose Luis García-Pérez, John L. Goodier
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Mobile DNA
Online Access:http://link.springer.com/article/10.1186/s13100-018-0138-z

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http://link.springer.com/article/10.1186/s13100-018-0138-z

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