Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis
ABSTRACT Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving loss of motor neurons and having no known cure and uncertain etiology. Several studies have drawn connections between altered retrotransposon expression and ALS. Certain features of the LINE-1 (L1)...
Main Authors: | Gavin C. Pereira, Laura Sanchez, Paul M. Schaughency, Alejandro Rubio-Roldán, Jungbin A. Choi, Evarist Planet, Ranjan Batra, Priscilla Turelli, Didier Trono, Lyle W. Ostrow, John Ravits, Haig H. Kazazian, Sarah J. Wheelan, Sara R. Heras, Jens Mayer, Jose Luis García-Pérez, John L. Goodier |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-12-01
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Series: | Mobile DNA |
Online Access: | http://link.springer.com/article/10.1186/s13100-018-0138-z |
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