Characterization of CD44 intracellular domain interaction with RUNX2 in PC3 human prostate cancer cells

Characterization of CD44 intracellular domain interaction with RUNX2 in PC3 human prostate cancer cells

Abstract Background Expression of CD44 receptor is associated with the onset of several tumors. The intracellular domain of CD44 (CD44-ICD) has been implicated as a co-transcription factor for RUNX2 in the regulation of expression of MMP-9 in breast carcinoma cells. Previous studies from our laborat...

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Bibliographic Details
Main Authors: Linda T. Senbanjo, Hanan AlJohani, Sunipa Majumdar, Meenakshi A. Chellaiah
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Cell Communication and Signaling
Subjects:
Prostate cancer
Metastasis
CD44
RUNX2
CD44-ICD
MMP-9
Online Access:http://link.springer.com/article/10.1186/s12964-019-0395-6

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http://link.springer.com/article/10.1186/s12964-019-0395-6

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