Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin.

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin.

Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated with repetitive sequences enriched in PCH geno...

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Bibliographic Details
Main Authors: Yuh Chwen G Lee, Yuki Ogiyama, Nuno M C Martins, Brian J Beliveau, David Acevedo, C-Ting Wu, Giacomo Cavalli, Gary H Karpen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008673

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https://doi.org/10.1371/journal.pgen.1008673

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