VEGFR2 translocates to the nucleus to regulate its own transcription.

VEGFR2 translocates to the nucleus to regulate its own transcription.

Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) is the major mediator of the angiogenic effects of VEGF. In addition to its well known role as a membrane receptor that activates multiple signaling pathways, VEGFR2 also has a nuclear localization. However, what VEGFR2 does in the nucleus is st...

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Bibliographic Details
Main Authors: Inês Domingues, José Rino, Jeroen A A Demmers, Primal de Lanerolle, Susana Constantino Rosa Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182252?pdf=render

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http://europepmc.org/articles/PMC3182252?pdf=render

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