Impact of corvitin and alpha-ketoglutarate on heart morphology, expression and activity of matrix metalloproteinases 2/9 in the heart of rats with doxorubicin-induced cardiomyopathy
The anthracycline anticancer drug doxorubicin is an effective and frequently used chemotherapeutic agent for various malignancies but it causes acute ventricular dysfunction, and also induces cardiomyopathy and heart failure. One of the mechanisms of cardiotoxicity of doxorubicin is oxidative stress...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Oles Honchar Dnipro National University
2019-10-01
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| Series: | Regulatory Mechanisms in Biosystems |
| Subjects: | |
| Online Access: | https://medicine.dp.ua/index.php/med/article/view/556 |