Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes.

Anti-hepatitis C virus (HCV) cross-neutralizing human monoclonal antibodies, directed against conserved epitopes on surface E2 glycoprotein, are central tools for understanding virus-host interplay, and for planning strategies for prevention and treatment of this infection. Recently, we developed a...

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Bibliographic Details
Main Authors: Nicasio Mancini, Roberta A Diotti, Mario Perotti, Giuseppe Sautto, Nicola Clementi, Giovanni Nitti, Arvind H Patel, Jonathan K Ball, Massimo Clementi, Roberto Burioni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2785886?pdf=render