Genome Plasticity and Polymorphisms in Critical Genes Correlate with Increased Virulence of Dutch Outbreak-Related Coxiella burnetii Strains

Genome Plasticity and Polymorphisms in Critical Genes Correlate with Increased Virulence of Dutch Outbreak-Related Coxiella burnetii Strains

Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. During 2007–2010 the largest Q fever outbreak ever reported occurred in The Netherlands. It is anticipated that strains from this outbreak demonstrated an increased zoonotic potential as more than 40,000 i...

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Bibliographic Details
Main Authors: Runa Kuley, Eric Kuijt, Mari A. Smits, Hendrik I. J. Roest, Hilde E. Smith, Alex Bossers
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
C. burnetii
Q fever
whole genome sequencing
comparative genomics
virulence
transposons
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01526/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01526/full

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