Vulnerable Plaque Detection and Quantification with Gold Particle–Enhanced Computed Tomography in Atherosclerotic Mouse Models

Recently, an apolipoprotein E–deficient (ApoE −/− ) mouse model with a mutation (C1039G+/−) in the fibrillin-1 ( Fbn1 ) gene (ApoE −/− Fbn1 C1039G+/− mouse model) was developed showing vulnerable atherosclerotic plaques, prone to rupture, in contrast to the ApoE −/− mouse model, where mainly stable...

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Bibliographic Details
Main Authors: David De Wilde, Bram Trachet, Carole Van der Donckt, Bert Vandeghinste, Benedicte Descamps, Christian Vanhove, Guido R. Y. De Meyer, Patrick Segers
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-06-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2015.00009