Refining the <i>Galleria mellonella</i> Model by Using Stress Marker Genes to Assess <i>Clostridioides difficile</i> Infection and Recuperation during Phage Therapy

Refining the <i>Galleria mellonella</i> Model by Using Stress Marker Genes to Assess <i>Clostridioides difficile</i> Infection and Recuperation during Phage Therapy

The <i>Galleria mellonella</i> is an effective model for probing <i>Clostridioides difficile</i> interactions with phages. Despite valuable insights from this model, the larvae are not easily amenable to assessing detailed clinical responses to either bacteria or phages. Here...

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Bibliographic Details
Main Authors: Janet Y. Nale, Mahananda Chutia, Jeffrey K. J. Cheng, Martha R. J. Clokie
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Microorganisms
Subjects:
<i>Clostridioides difficile</i>
<i>Clostridium difficile</i>
<i>Clostridiodes difficile</i> infection
<i>Galleria mellonella</i>
bacteriophage therapy
qPCR
Online Access:https://www.mdpi.com/2076-2607/8/9/1306

Internet

https://www.mdpi.com/2076-2607/8/9/1306

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