ELK1-induced upregulation of long non-coding RNA MIR100HG predicts poor prognosis and promotes the progression of osteosarcoma by epigenetically silencing LATS1 and LATS2

ELK1-induced upregulation of long non-coding RNA MIR100HG predicts poor prognosis and promotes the progression of osteosarcoma by epigenetically silencing LATS1 and LATS2

Osteosarcoma (OS) is the commonest malignant bone tumor in the world. High incidence of OS has gradually become a social problem. Recent years, numerous studies have revealed that long non-coding RNAs (lncRNAs) are crucial regulators in the tumor progression. As a member of lncRNA family, MIR100HG h...

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Bibliographic Details
Main Authors: Xiaochuan Su, Junyan Teng, Guoguo Jin, Jitian Li, Zhenjiang Zhao, Xiangyang Cao, Yanxing Guo, Malong Guo, Xiaoling Li, Jun Wu, Chuanzhen Wang, Zhiping Guo, Qing Guo
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
MIR100HG
ELK1
Hippo signaling pathway
Proliferation
Osteosarcoma
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221835964X

Internet

http://www.sciencedirect.com/science/article/pii/S075333221835964X

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