An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility.

Papillary Thyroid Cancer (PTC) is a heterogeneous and complex disease; susceptibility to PTC is influenced by the joint effects of multiple common, low-penetrance genes, although relatively few have been identified to date. Here we applied a rigorous combined approach to assess both the individual a...

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Main Authors: Iñigo Landa, Cesar Boullosa, Lucía Inglada-Pérez, Ana Sastre-Perona, Susana Pastor, Antonia Velázquez, Veronika Mancikova, Sergio Ruiz-Llorente, Francesca Schiavi, Ricard Marcos, Nuria Malats, Giuseppe Opocher, Ramon Diaz-Uriarte, Pilar Santisteban, Alfonso Valencia, Mercedes Robledo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781145?pdf=render