Dissecting human trophoblast cell transcriptional heterogeneity in preeclampsia using single‐cell RNA sequencing

Dissecting human trophoblast cell transcriptional heterogeneity in preeclampsia using single‐cell RNA sequencing

Abstract Objective PE is a pregnancy‐specific syndrome that affects 3%–5% of pregnant women. It often presents as new‐onset hypertension and proteinuria during the third trimester. PE progresses rapidly and may lead to serious complications, including the death of both mother and fetus. In low‐incom...

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Bibliographic Details
Main Authors: Tao Zhang, Qianqian Bian, Yanchun Chen, Xiaolin Wang, Shaowei Yu, Shunhua Liu, Ping Ji, Ling Li, Mandakini Shrestha, Shujun Dong, Rong Guo, Hong Zhang
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
extravillous trophoblasts
preeclampsia
single‐cell RNA sequencing
syncytiotrophoblast
villi cytotrophoblast
Online Access:https://doi.org/10.1002/mgg3.1730

Internet

https://doi.org/10.1002/mgg3.1730

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