Identification of Key Residues for Enzymatic Carboxylate Reduction

Identification of Key Residues for Enzymatic Carboxylate Reduction

Carboxylate reductases (CARs, E.C. 1.2.1.30) generate aldehydes from their corresponding carboxylic acid with high selectivity. Little is known about the structure of CARs and their catalytically important amino acid residues. The identification of key residues for carboxylate reduction provides a s...

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Bibliographic Details
Main Authors: Holly Stolterfoht, Georg Steinkellner, Daniel Schwendenwein, Tea Pavkov-Keller, Karl Gruber, Margit Winkler
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Microbiology
Subjects:
carboxylate reductase
biocatalysis
signature sequence
aldehyde
flavor and fragrance
pharmaceutical intermediate
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00250/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00250/full

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