TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo.

BACKGROUND:TM4SF1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and affects the development of this cancer. Also, multidrug resistance (MDR) is generally associated with tumor chemoresistance in pancreatic cancer. However, the correlation between TM4SF1 and MDR remains unknown. This re...

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Bibliographic Details
Main Authors: Jia Cao, Jiachun Yang, Vijaya Ramachandran, Thiruvengadam Arumugam, Defeng Deng, Zhaoshen Li, Leiming Xu, Craig D Logsdon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4692438?pdf=render