A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy.

A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy.

Herpes simplex virus type-2 (HSV-2) infection enhances the transmission and acquisition of human immunodeficiency virus (HIV). This occurs in symptomatic and asymptomatic stages of HSV-2 infection, suggesting that obvious herpetic lesions are not required to increase HIV spread. An animal model to i...

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Bibliographic Details
Main Authors: Federica Crostarosa, Meropi Aravantinou, Onome J Akpogheneta, Edith Jasny, Andrew Shaw, Jessica Kenney, Michael Piatak, Jeffrey D Lifson, Aaron Teitelbaum, Lieyu Hu, Anne Chudolij, Thomas M Zydowsky, James Blanchard, Agegnehu Gettie, Melissa Robbiani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2787245?pdf=render

Internet

http://europepmc.org/articles/PMC2787245?pdf=render

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