Cardiac macrophages prevent sudden death during heart stress

Cardiac macrophages prevent sudden death during heart stress

Cardiac immune cells play various roles in the maintenance of homeostasis and diseases in the heart. Here the authors show that cardiac resident macrophages are a critical regulator of cardiac impulse conduction through amphiregulin production, contributing to the prevention of sudden death.

Bibliographic Details
Main Authors: Junichi Sugita, Katsuhito Fujiu, Yukiteru Nakayama, Takumi Matsubara, Jun Matsuda, Tsukasa Oshima, Yuxiang Liu, Yujin Maru, Eriko Hasumi, Toshiya Kojima, Hiroshi Seno, Keisuke Asano, Ayumu Ishijima, Naoki Tomii, Masatoshi Yamazaki, Fujimi Kudo, Ichiro Sakuma, Ryozo Nagai, Ichiro Manabe, Issei Komuro
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22178-0

Internet

https://doi.org/10.1038/s41467-021-22178-0

Similar Items