Hyperbaric oxygen promotes osteogenic differentiation of bone marrow stromal cells by regulating Wnt3a/β-catenin signaling—An in vitro and in vivo study

We hypothesized that the effect of hyperbaric oxygen (HBO) on bone formation is increased via osteogenic differentiation of bone marrow stromal cells (BMSCs), which is regulated by Wnt3a/β-catenin signaling. Our in vitro data showed that HBO increased cell proliferation, Wnt3a production, LRP6 phosp...

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Bibliographic Details
Main Authors: Song-Shu Lin, Steve W.N. Ueng, Chi-Chien Niu, Li-Jen Yuan, Chuen-Yung Yang, Wen-Jer Chen, Mel S. Lee, Jan-Kan Chen
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506113001578