Knockdown of ANGPTL2 Protects Renal Tubular Epithelial Cells Against Hypoxia/Reoxygenation-Induced Injury via Suppressing TLR4/NF-κB Signaling Pathway and Activating Nrf2/HO-1 Signaling Pathway

Knockdown of ANGPTL2 Protects Renal Tubular Epithelial Cells Against Hypoxia/Reoxygenation-Induced Injury via Suppressing TLR4/NF-κB Signaling Pathway and Activating Nrf2/HO-1 Signaling Pathway

Renal ischemia/reperfusion (I/R) injury is a particular threat faced by clinicians in kidney transplantation. Previous studies have confirmed the importance of oxidative stress and inflammation in the pathogenesis of I/R injury. Angiopoietin-like protein 2 (ANGPTL2) belongs to the angiopoietin-like...

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Bibliographic Details
Main Authors: Heli Xiang, Wujun Xue, Yang Li, Jin Zheng, Chenguang Ding, Meng Dou, Xiaoyan Wu
Format: Article
Language:English
Published: SAGE Publishing 2020-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689720946663

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https://doi.org/10.1177/0963689720946663

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