Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration
Abstract Background Retinal degenerative diseases significantly contribute to visual impairment and blindness. Microglia reactivity is a hallmark of neurodegenerative diseases including retinal cell death and immunomodulation emerges as a therapeutic option. Indole-3-carbinol (I3C) is a natural liga...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-11-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-020-01999-8 |