Novel Protein-Based Pneumococcal Vaccines: Assessing the Use of Distinct Protein Fragments Instead of Full-Length Proteins as Vaccine Antigens

Non-serotype-specific protein-based pneumococcal vaccines have received extensive research focus due to the limitations of polysaccharide-based vaccines. Pneumococcal proteins (PnPs), universally expressed among serotypes, may induce broader immune responses, stimulating humoral and cellular immunit...

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Bibliographic Details
Main Authors: Theano Lagousi, Paraskevi Basdeki, John Routsias, Vana Spoulou
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/7/1/9