Integrating ion mobility mass spectrometry with molecular modelling to determine the architecture of multiprotein complexes.

Integrating ion mobility mass spectrometry with molecular modelling to determine the architecture of multiprotein complexes.

Current challenges in the field of structural genomics point to the need for new tools and technologies for obtaining structures of macromolecular protein complexes. Here, we present an integrative computational method that uses molecular modelling, ion mobility-mass spectrometry (IM-MS) and incompl...

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Bibliographic Details
Main Authors: Argyris Politis, Ah Young Park, Suk-Joon Hyung, Daniel Barsky, Brandon T Ruotolo, Carol V Robinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2919415?pdf=render

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http://europepmc.org/articles/PMC2919415?pdf=render

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