Deficiency of peroxisome proliferator-activated receptor α attenuates apoptosis and promotes migration of vascular smooth muscle cells

Deficiency of peroxisome proliferator-activated receptor α attenuates apoptosis and promotes migration of vascular smooth muscle cells

Peroxisome proliferator-activated receptor (PPAR) α is widely expressed in the vasculature and has pleiotropic and lipid-lowering independent effects, but its role in the growth and function of vascular smooth muscle cells (VSMCs) during vascular pathophysiology is still unclear. Herein, VSMC-specif...

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Bibliographic Details
Main Authors: Yan Duan, Dan Qi, Ye Liu, Yanting Song, Xia Wang, Shiyu Jiao, Huihua Li, Frank J. Gonzalez, Yongfen Qi, Qingbo Xu, Jie Du, Aijuan Qu
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Angiotensin II
PPARα
Vascular remodeling
Vascular smooth muscle cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821001850

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http://www.sciencedirect.com/science/article/pii/S2405580821001850

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