Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence.

Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through interaction with a range of effecto...

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Bibliographic Details
Main Authors: Shi-qi An, Delphine L Caly, Yvonne McCarthy, Sarah L Murdoch, Joseph Ward, Melanie Febrer, J Maxwell Dow, Robert P Ryan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4199771?pdf=render