Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants: Post-hoc Analysis of Its Effect on Brain Injury

Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants: Post-hoc Analysis of Its Effect on Brain Injury

Background: Postnatal insulin-like growth factor-1 (IGF-1) replacement with recombinant human (rh)IGF-1 and IGF binding protein-3 (rhIGF-1/rhIGFBP-3) is being studied as a potential treatment to reduce comorbidities of prematurity. We have recently reported on a phase II, multicenter, randomized, co...

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Bibliographic Details
Main Authors: Sandra Horsch, Alessandro Parodi, Boubou Hallberg, Mariya Malova, Isabella M. Björkman-Burtscher, Ingrid Hansen-Pupp, Neil Marlow, Kathryn Beardsall, David Dunger, Mirjam van Weissenbruch, Lois E. H. Smith, Mohamed Hamdani, Alexandra Mangili, Norman Barton, Luca A. Ramenghi, Ann Hellström, David Ley, ROPP-2008-01 Study Team
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pediatrics
Subjects:
neonate
brain injury
cerebral hemorrhage
recombinant human IGF-1
extremely preterm
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.517207/full

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https://www.frontiersin.org/article/10.3389/fped.2020.517207/full

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