Pharmacokinetic interaction of riociguat and antiretroviral combination regimens in HIV-1-infected adults

Riociguat, a first-in-class soluble guanylate cyclase stimulator, is approved for the treatment of pulmonary arterial hypertension (PAH), a serious potential complication of human immunodeficiency virus (HIV) infection. This open-label study investigated the pharmacokinetic drug–drug interaction pot...

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Bibliographic Details
Main Authors: Edwin DeJesus, Soundos Saleh, Sue Cheng, Dorina van der Mey, Corina Becker, Reiner Frey, Sigrun Unger, Wolfgang Mueck
Format: Article
Language:English
Published: SAGE Publishing 2019-05-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894019848644