Electrospun Nanofiber Meshes With Endometrial MSCs Modulate Foreign Body Response by Increased Angiogenesis, Matrix Synthesis, and Anti-Inflammatory Gene Expression in Mice: Implication in Pelvic Floor

Electrospun Nanofiber Meshes With Endometrial MSCs Modulate Foreign Body Response by Increased Angiogenesis, Matrix Synthesis, and Anti-Inflammatory Gene Expression in Mice: Implication in Pelvic Floor

PurposeTransvaginal meshes for the treatment of Pelvic Organ Prolapse (POP) have been associated with severe adverse events and have been banned for clinical use in many countries. We recently reported the design of degradable poly L-lactic acid-co-poly ε-caprolactone nanofibrous mesh (P nanomesh) b...

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Bibliographic Details
Main Authors: Shayanti Mukherjee, Saeedeh Darzi, Kallyanashis Paul, Fiona L. Cousins, Jerome A. Werkmeister, Caroline E. Gargett
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
mesenchymal stem cells
pelvic organ prolapse
electrospinning
nanofiber mesh
tissue engineering
foreign body response
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00353/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00353/full

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